PT - JOURNAL ARTICLE AU - Tobias Gaster AU - Christine Marie Eggertsen AU - Henrik Støvring AU - Vera Ehrenstein AU - Irene Petersen TI - Quantifying the impact of unmeasured confounding in observational studies with the E value AID - 10.1136/bmjmed-2022-000366 DP - 2023 May 01 TA - BMJ Medicine PG - e000366 VI - 2 IP - 1 4099 - http://bmjmedicine.bmj.com/content/2/1/e000366.short 4100 - http://bmjmedicine.bmj.com/content/2/1/e000366.full SO - bmjmed2023 May 01; 2 AB - The E value method deals with unmeasured confounding, a key source of bias in observational studies. The E value method is described and its use is shown in a worked example of a meta-analysis examining the association between the use of antidepressants in pregnancy and the risk of miscarriage.Data sharing not applicable as no datasets generated and/or analysed for this study.