Table 2

Perinatal outcomes of singleton pregnancies, focusing on babies that died

Perinatal outcomesWhole cohort (n=326)*Gestational age at PPROM (weeks+days)Unadjusted relative rate ratio of outcome for each additional week of gestation at PPROM (RR (95% CI), P value)
16+0-17+6 (n=82)18+0-19+6 (n=102)20+0-21+6 (n=105)22+0-22+6 (n=37)
Termination for medical reasons without expectant management62 (19)25 (30)19 (19)17 (16)1 (3)0.75 (0.64 to 0.87), 0.001
Termination for medical reasons after expectant management41 (13)14 (17)13 (13)8 (8)6 (16)0.92 (0.77 to 1.09), 0.33
Birth or intrauterine death <22+0 weeks' gestation (miscarriage) (expectant management throughout pregnancy)90/223 (40)26/33 (79)37/70 (53)27/80 (34)0.80 (0.70 to 0.91), 0.001
Intrauterine deaths ≥22+0 weeks' gestation (expectant management throughout pregnancy)35/223 (16)3/33 (9)6/70 (9)16/80 (20)10/30 (33)1.59 (1.27 to 1.99), 0.001
Neonatal deaths (expectant management throughout pregnancy)28/223 (13)4/33 (12)8/70 (11)10/80 (13)6/30 (20)1.24 (1.00 to 1.53), 0.05
  • Data are No (%) or No/total No (%). CI=confidence interval; PPROM=preterm prelabour rupture of membranes; RR=relative rate.

  • *Gestational age at PPROM 16+0-22+6 weeks+days.