Table 2

Hazard ratios (95% confidence intervals) for each transition, for different transition patterns for progressive cardiovascular disease by regular use of fish oil supplements

Transition patternNo of eventsHazard ratio (95% CI)P value
Transition pattern I
 Baseline→atrial fibrillation18 3671.13 (1.10 to 1.17)<0.001
 Baseline→major adverse cardiovascular events17 8261.00 (0.97 to 1.04)0.819
 Baseline→death14 9020.98 (0.95 to 1.02)0.280
 Atrial fibrillation→major adverse cardiovascular events48100.92 (0.87 to 0.98)0.008
 Atrial fibrillation→death16530.91 (0.82 to 1.01)0.680
 Major adverse cardiovascular events→death55850.99 (0.94 to 1.06)0.937
Transition pattern II
 Baseline→atrial fibrillation18 3671.13 (1.10 to 1.17)<0.001
 Baseline→heart failure45520.92 (0.86 to 0.98)0.011
 Baseline→death17 5800.99 (0.96 to 1.02)0.655
 Atrial fibrillation→heart failure30850.95 (0.88 to 1.02)0.162
 Atrial fibrillation→death21240.89 (0.82 to 0.98)0.016
 Heart failure→death24360.91 (0.84 to 0.99)0.040
Transition pattern III
 Baseline→atrial fibrillation18 3671.13 (1.10 to 1.17)<0.001
 Baseline→stroke60981.05 (1.00 to 1.11)0.050
 Baseline→death17 4000.97 (0.94 to 1.01)0.131
 Atrial fibrillation→stroke11801.00 (0.89 to 1.13)0.983
 Atrial fibrillation→death26520.91 (0.84 to 0.99)0.021
 Stroke→death20881.04 (0.95 to 1.14)0.347
Transition pattern IV
 Baseline→atrial fibrillation18 3671.13 (1.10 to 1.17)<0.001
 Baseline→myocardial infarction93001.01 (0.96 to 1.05)0.711
 Baseline→death17 3780.98 (0.95 to 1.01)0.235
 Atrial fibrillation→myocardial infarction14150.85 (0.76 to 0.96)0.006
 Atrial fibrillation→death26640.88 (0.81 to 0.95)0.002
 Myocardial infarction→death20981.03 (0.94 to 1.13)0.510
  • Model adjusted for age, sex, ethnic group, Townsend deprivation index, consumption of oily fish, consumption of non-oily fish, smoking status, consumption of alcohol, obesity, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic renal failure, and use of statins, antidiabetic drugs, and antihypertensive drugs.

  • CI, confidence interval.