Table 2

Age and sex specific cut-off values for stratifying individuals at high risk of cardiovascular disease, and numbers of individuals identified as high risk in different strategies with risk estimations by version 2 of the QRISK cardiovascular disease risk algorithm (QRISK2)

Age (years)MenWomen
Strategy A*Strategy B†Strategy A*Strategy B†
Cut-off (%)No (%)Cut-off (%)No (%)Cut-off (%)No (%)Cut-off (%)No (%)
4010300 (1.3)5.02234 (10.0)‡1081 (0.4)3.02127 (10.0)‡
4110406 (1.8)5.52204 (10.0)‡1099 (0.5)3.32143 (10.0)‡
4210490 (2.3)6.02162 (10.0)‡10121 (0.6)3.62063 (10.0)‡
4310627 (3.0)6.72073 (10.0)‡10151 (0.8)4.02012 (10.0)‡
4410778 (3.8)7.32023 (10.0)‡10198 (1.0)4.41975 (10.0)‡
45101010 (5.1)8.11962 (10.0)§10224 (1.2)4.71918 (10.0)‡
46101283 (6.8)8.81886 (10.0)§10264 (1.4)5.21824 (10.0)‡
47101653 (9.0)9.71834 (10.0)§10338 (1.9)5.71818 (10.0)‡
48102059 (11.7)102059 (11.7)10414 (2.4)6.21754 (10.0)‡
49102509 (15.0)102509 (15.0)10475 (2.8)6.61685 (10.0)‡
50103150 (19.9)103150 (19.9)10566 (3.6)7.21583 (10.0)‡
51103806 (24.6)103806 (24.6)10723 (4.5)7.81590 (10.0)§
52104764 (31.0)104764 (31.0)10872 (5.5)8.31586 (10.0)§
53105694 (38.1)105694 (38.1)101022 (6.7)8.91535 (10.0)§
54106700 (46.6)106700 (46.6)101330 (8.8)101507 (10.0)
55107878 (54.9)107878 (54.9)101702 (11.3)101702 (11.3)
56109242 (63.2)109242 (63.2)102132 (13.9)102132 (13.9)
571010 735 (71.6)1010 735 (71.6)102796 (17.6)102796 (17.6)
581013 024 (79.7)1013 024 (79.7)103807 (21.7)103807 (21.7)
591012 600 (86.9)1012 600 (86.9)104294 (27.3)104294 (27.3)
601010 711 (92.7)1010 711 (92.7)104174 (33.5)104174 (33.5)
611011 897 (96.7)1011 897 (96.7)105455 (41.2)105455 (41.2)
621010 577 (98.8)1010 577 (98.8)106115 (50.6)106115 (50.6)
63109943 (99.7)109943 (99.7)106607 (60.1)106607 (60.1)
64108296 (99.9)108296 (99.9)106593 (69.4)106593 (69.4)
65107843 (100.0)107843 (100.0)107225 (78.6)107225 (78.6)
66107740 (100.0)107740 (100.0)108159 (87.4)108159 (87.4)
67107489 (100.0)107489 (100.0)108330 (93.8)108330 (93.8)
68106980 (100.0)106980 (100.0)108255 (97.8)108255 (97.8)
69106421 (100.0)106421 (100.0)108036 (99.6)108036 (99.6)
70105823 (100.0)105823 (100.0)107967 (99.9)107967 (99.9)
71105550 (100.0)105550 (100.0)107417 (100.0)107417 (100.0)
72105044 (100.0)105044 (100.0)106912 (100.0)106912 (100.0)
73104837 (100.0)104837 (100.0)106884 (100.0)106884 (100.0)
74104670 (100.0)104670 (100.0)106689 (100.0)106689 (100.0)
75104488 (100.0)104488 (100.0)106710 (100.0)106710 (100.0)
76104077 (100.0)104077 (100.0)106313 (100.0)106313 (100.0)
77103883 (100.0)103883 (100.0)106019 (100.0)106019 (100.0)
78103483 (100.0)103483 (100.0)105642 (100.0)105642 (100.0)
79103316 (100.0)103316 (100.0)105325 (100.0)105325 (100.0)
80103119 (100.0)103119 (100.0)105162 (100.0)105162 (100.0)
81102816 (100.0)102816 (100.0)105019 (100.0)105019 (100.0)
82102663 (100.0)102663 (100.0)104939 (100.0)104939 (100.0)
83102290 (100.0)102290 (100.0)104747 (100.0)104747 (100.0)
84102221 (100.0)102221 (100.0)104565 (100.0)104565 (100.0)
85102137 (100.0)102137 (100.0)104558 (100.0)104558 (100.0)
  • *Strategy A identified individuals with a high risk of cardiovascular disease as those with an estimated 10 year risk of cardiovascular disease ≥10% (fixed threshold).

  • †Strategy B identified individuals with a high risk of cardiovascular disease as those with an estimated 10 year risk of cardiovascular disease ≥10% or ≥90th centile of age and sex specific risk distributions (age and sex specific thresholds).

  • ‡Cut-off values <7.5%.

  • §Cut-off values ≥7.5% and <10%.