Table 1

Grading criteria for evidence categories from meta-analyses of summary level data included in review. Evidence relates to the strength of associations between environmental risk factors and risk of non-Hodgkin's lymphoma

Strength of associationDescription*
ConvincingHighly significant association (P<0.000001)
At least 1000 cases of non-Hodgkin's lymphoma
Low or moderate proportion of total variability due to variability between studies (I2 <50%)
95% prediction interval excluding the null value
Largest study reporting a nominally significant result (P<0.05)
No evidence of small study effects
No evidence of excess significance bias
Highly suggestiveHighly significant association (P<0.000001)
At least 1000 non-Hodgkin's lymphoma cases
Largest study reporting a nominally significant result (P<0.05)
SuggestiveAt least 1000 non-Hodgkin's lymphoma cases
Significant association (P<0.001)
WeakNominally significant association (P<0.05)
Non-significantNon-significant associations (P>0.05)
  • *P value for the association from a random effects model.