Pregnancy outcomes for women admitted with SARS-CoV-2 infection during the period when omicron was the dominant variant, by symptom group and vaccination status in the UK between 15 December 2021 and 14 March 2022
Vaccination status | With symptoms (n=986; No (%) | Without symptoms (n=2713; No (%)) | ||||||||
Unvaccinated (n=489) | One dose (n=107) | Two doses (n=194) | Three doses (n=55) | Unknown (n=141) | Unvaccinated (n=1397) | One dose (n=226) | Two doses (n=140) | Three doses (n=140) | Unknown (n=494) | |
Known to have been discharged still pregnant* | 144 (29.5) | 32 (29.9) | 65 (33.5) | 21 (38.2) | 52 (36.9) | 127 (9.1) | 25 (11.1) | 49 (10.8) | 12 (8.6) | 80 (16.2) |
Still pregnant, not known to have been discharged* | 55 (11.3) | 7 (6.5) | 28 (14.4) | 7 (12.7) | 18 (12.8) | 80 (5.7) | 9 (4.0) | 21 (4.6) | 4 (2.9) | 21 (4.3) |
Pregnancy outcome known:† | 289 (59.2) | 68 (63.6) | 101 (52.1) | 27 (49.1) | 71 (50.4) | 1190 (85.2) | 192 (85.0) | 386 (84.7) | 124 (88.6) | 393 (79.6) |
Pregnancy loss | 5 (1.0) | 1 (0.9) | 1 (0.5) | 0 (0.0) | 3 (2.1) | 23 (1.7) | 2 (0.9) | 9 (2.0) | 5 (3.6) | 13 (2.6) |
Birth | 284 (58.1) | 67 (62.6) | 100 (51.6) | 27 (49.1) | 68 (48.2) | 1167 (83.5) | 190 (84.1) | 377 (82.7) | 119 (85.0) | 380 (76.9) |
Gestation at birth (weeks+days):‡ | ||||||||||
<22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (0.3) | 0 | 0 |
22+0-27+6 | 1 (0.4) | 1 (1.5) | 2 (2.0) | 0 | 0 | 8 (0.7) | 1 (0.5) | 3 (0.8) | 1 (0.9) | 2 (0.5) |
28+0-33+6 | 11 (3.9) | 1 (1.5) | 4 (4.0) | 0 | 4 (6.0) | 24 (2.1) | 7 (3.7) | 11 (2.9) | 0 (0.0) | 6 (1.6) |
34+0-36+6 | 42 (14.8) | 3 (4.6) | 11 (11.1) | 2 (7.4) | 5 (7.4) | 92 (7.9) | 16 (8.4) | 26 (6.9) | 8 (6.7) | 32 (8.6) |
37+0 or more | 230 (81.0) | 61 (92.4) | 82 (82.8) | 25 (92.6) | 59 (86.8) | 1038 (89.3) | 166 (87.4) | 334 (89.1) | 110 (92.4) | 334 (89.3) |
Missing | 0 | 1 | 1 | 0 | 0 | 5 | 0 | 2 | 0 | 6 |
Birth expedited due to covid-19‡ | 17 (6.0) | 1 (1.5) | 2 (2.0) | 0 | 3 (4.4) | 0 | 0 | 0 | 0 | 0 |
Mode of birth:‡ | ||||||||||
Caesarean before labour onset | 78 (27.6) | 27 (40.9) | 25 (25.3) | 5 (18.5) | 23 (33.8) | 255 (21.9) | 45 (23.7) | 116 (30.9) | 35 (29.4) | 89 (23.6) |
Caesarean after labour onset | 44 (15.6) | 15 (22.7) | 11 (11.1) | 4 (14.8) | 9 (13.2) | 184 (15.8) | 28 (14.7) | 56 (14.9) | 17 (14.3) | 40 (10.6) |
Operative vaginal | 24 (8.5) | 4 (6.1) | 13 (13.1) | 4 (14.8) | 5 (7.4) | 142 (12.2) | 16 (8.4) | 36 (9.6) | 18 (15.1) | 46 (12.2) |
Unassisted vaginal | 137 (48.4) | 20 (30.3) | 50 (50.5) | 14 (51.9) | 31 (45.6) | 583 (50.1) | 101 (53.2) | 167 (44.5) | 49 (41.2) | 202 (53.6) |
Missing | 1 | 1 | 1 | 0 | 0 | 3 | 0 | 2 | 0 | 3 |
*Excluding one woman who died while still pregnant.
†Pregnancy outcome information received by UKOSS in primary report or in supplementary update before19 April 2022
‡ Births to women with known pregnancy outcome as denominator, excluding pregnancy loss.