Table 3

Risk of attrition for trial by mean trial comorbidity count, according to risk of attrition in those individuals with no comorbidities

Baseline risk (%) of trial attrition (ie, assumed risk in those individuals with no comorbidities)Mean comorbidity count in trial (% with two or more comorbidities)
0.5 (1%)0.751 (8%)1.252 (32%)
566667
151718181820
252829293031
353939404142
454950505153
  • Estimated proportion of trial participants likely to withdraw early based on the probability of termination among individuals with no comorbidities and the mean comorbidity count. Assumes odds ratio of 1.1 for attrition per one unit increment in comorbidity count (see results) and that the comorbidity count is Poisson distributed. See online supplemental appendix for detailed steps.