Median (interquartile range) percentage of overlap in outcomes between pairs of core outcome sets (COS) and matching guidance documents from the European Medicines Agency (EMA) and US Food and Drug Administration (FDA)
| Pairs | Specific matches (%) | General matches (%) | Specific or general matches (%) |
| COS and EMA (n=44) | 46 (27-68) | 13 (0-27) | 70 (48-86) |
| COS and FDA (n=30) | 26 (18-46) | 11 (0-37) | 52 (33-77) |