User profiles for "author:Bruce Guthrie"

Bruce Guthrie

University of Edinburgh
Verified email at ed.ac.uk
Cited by 31823

Designing and evaluating complex interventions to improve health care

NC Campbell, E Murray, J Darbyshire, J Emery… - Bmj, 2007 - bmj.com
Designing and evaluating complex interventions to improve health care | The BMJ Skip to main
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Managing patients with multimorbidity in primary care

E Wallace, C Salisbury, B Guthrie, C Lewis, T Fahey… - Bmj, 2015 - bmj.com
Multimorbidity, commonly defined as the presence of two or more chronic medical conditions
in an individual, 1 is associated with decreased quality of life, functional decline, and …

Multimorbidity

ST Skou, FS Mair, M Fortin, B Guthrie… - Nature Reviews …, 2022 - nature.com
Multimorbidity (two or more coexisting conditions in an individual) is a growing global
challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a …

[HTML][HTML] Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study

K Barnett, SW Mercer, M Norbury, G Watt, S Wyke… - The Lancet, 2012 - thelancet.com
Background Long-term disorders are the main challenge facing health-care systems
worldwide, but health systems are largely configured for individual diseases rather than …

Continuity in UK general practice: a multilevel model of patient, doctor and practice factors associated with patients seeing their usual doctor

B Guthrie - Family Practice, 2002 - academic.oup.com
Background. Personal continuity is a 'core value'for UK general practice, but often appears
ignored by organizational change. Objectives. The aim of the present study was to examine …

[HTML][HTML] Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study

A Clark, M Jit, C Warren-Gash, B Guthrie… - The Lancet Global …, 2020 - thelancet.com
Background The risk of severe COVID-19 if an individual becomes infected is known to be
higher in older individuals and those with underlying health conditions. Understanding the …

[HTML][HTML] The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995–2010

B Guthrie, B Makubate, V Hernandez-Santiago… - BMC medicine, 2015 - Springer
Background The escalating use of prescribed drugs has increasingly raised concerns about
polypharmacy. This study aims to examine changes in rates of polypharmacy and potentially …

Adapting clinical guidelines to take account of multimorbidity

B Guthrie, K Payne, P Alderson, MET McMurdo… - Bmj, 2012 - bmj.com
ANALYSIS Page 1 Adapting clinical guidelines to take account of multimorbidity Care of patients
with multimorbidity could be improved if new technology is used to bring together guidelines …

Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity

LD Hughes, MET McMurdo, B Guthrie - Age and ageing, 2013 - academic.oup.com
Background: currently one of the major challenges facing clinical guidelines is
multimorbidity. Current guidelines are not designed to consider the cumulative impact of …

[HTML][HTML] Process evaluations for cluster-randomised trials of complex interventions: a proposed framework for design and reporting

A Grant, S Treweek, T Dreischulte, R Foy, B Guthrie - Trials, 2013 - Springer
Background Process evaluations are recommended to open the 'black box'of complex
interventions evaluated in trials, but there is limited guidance to help researchers design …