There are two popular statistical models for meta‐analysis, the fixed‐effect model and the
random‐effects model. The fact that these two models employ similar sets of formulas to …

When we speak about heterogeneity in a meta‐analysis, our intent is usually to understand
the substantive implications of the heterogeneity. If an intervention yields a mean effect size …

A clear and thorough introduction to meta-analysis, the process of synthesizing data from a
series of separate studies The first edition of this text was widely acclaimed for the clarity of …

In any meta-analysis, we start with summary data from each study and use it to compute an
effect size for the study. An effect size is a number that reflects the magnitude of the …

Comprehensive Meta‐Analysis (CMA) is a computer program for meta‐analysis that was
developed with funding from the National Institutes of Health in the United States. CMA features …

Objective: Recent, large, randomized controlled trials (RCTs) showed no benefit of long-acting
injectable (LAI) antipsychotics over oral antipsychotics in preventing relapse in …

If all studies in the analysis were equally precise we could simply compute the mean of the
effect sizes. However, if some studies were more precise than others we would want to assign …

… In Chapter 11, Michael Borenstein discusses a number of computer programs that can be
used to address publication bias, and shows how these would be used to apply the statistical …

Subgroup analysis is the process of comparing a treatment effect for two or more variants of
an intervention—to ask, for example, if an intervention’s impact is affected by the setting (…

Background: While long-acting injectable antipsychotics (LAIs) are hoped to reduce high
relapse rates in schizophrenia, recent randomized controlled trials (RCTs) challenged the …